论文标题

在实时心脏磁共振成像中自动提取和符号确定呼吸信号

Automatic Extraction and Sign Determination of Respiratory Signal in Real-time Cardiac Magnetic Resonance imaging

论文作者

Chen, Chong, Liu, Yingmin, Simonetti, Orlando P., Ahmad, Rizwan

论文摘要

实时(RT)心脏电影成像,在自由呼吸条件下依次收集了2D切片的堆栈。然后将每个切片的完整心跳用于心脏功能定量。切片间呼吸不匹配会损害心脏功能的准确定量。已经提出了基于主成分分析(PCA)的方法来从RT心脏CINE提取呼吸信号,但是这些方法无法解决呼吸信号的切片间符号歧义。在这项工作中,我们根据相邻切片的相似性以及与质量曲线的相关性提出了一个全自动符号校正程序。提出的方法在11名志愿者中进行评估,每个志愿者有十片。手动选择区域(ROI)中的运动用作参考。结果表明,在所有情况下,提取的呼吸信号与参考均具有高,正相关。对图像的定性评估还表明,所提出的方法可以准确地识别属于同一呼吸阶段的每个切片中的心跳。这种方法可以改善RT CINE的心脏功能定量,而无需手动干预。

In real-time (RT) cardiac cine imaging, a stack of 2D slices is collected sequentially under free-breathing conditions. A complete heartbeat from each slice is then used for cardiac function quantification. The inter-slice respiratory mismatch can compromise accurate quantification of cardiac function. Methods based on principal components analysis (PCA) have been proposed to extract the respiratory signal from RT cardiac cine, but these methods cannot resolve the inter-slice sign ambiguity of the respiratory signal. In this work, we propose a fully automatic sign correction procedure based on the similarity of neighboring slices and correlation to the center-of-mass curve. The proposed method is evaluated in eleven volunteers, with ten slices per volunteer. The motion in a manually selected region-of-interest (ROI) is used as a reference. The results show that the extracted respiratory signal has a high, positive correlation with the reference in all cases. The qualitative assessment of images also shows that the proposed approach can accurately identify heartbeats, one from each slice, belonging to the same respiratory phase. This approach can improve cardiac function quantification for RT cine without manual intervention.

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