论文标题

APTER:通过指数重新加权的总预后

APTER: Aggregated Prognosis Through Exponential Reweighting

论文作者

Pelckmans, Kristiaan, Yang, Liu

论文摘要

本文考虑了学习如何根据患者的微阵列表达水平进行预后的任务。该方法是关于理论机器学习的文献中最近提出的聚合方法的应用,并在其计算方便和能力方面擅长处理高维数据。给出了该方法的正式分析,产生类似于传统技术获得的收敛速率,同时证明可以很好地应对成倍的大型功能。这些结果由数值模拟支持一系列公开生存 - 阵列数据集。从经验上发现,所提出的技术与最近提出的预处理技术相结合提供了出色的性能。

This paper considers the task of learning how to make a prognosis of a patient based on his/her micro-array expression levels. The method is an application of the aggregation method as recently proposed in the literature on theoretical machine learning, and excels in its computational convenience and capability to deal with high-dimensional data. A formal analysis of the method is given, yielding rates of convergence similar to what traditional techniques obtain, while it is shown to cope well with an exponentially large set of features. Those results are supported by numerical simulations on a range of publicly available survival-micro-array datasets. It is empirically found that the proposed technique combined with a recently proposed preprocessing technique gives excellent performances.

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