学术文献库

Emerging infectious diseases are existential threats to human health and global stability. The recent outbreaks of the novel coronavirus COVID-19 have rapidly formed a global pandemic, causing hundreds of thousands of infections and huge economic loss. The WHO declares that more precise measures to track, detect and isolate infected people are among the most effective means to quickly contain the outbreak. Based on trajectory provided by the big data and the mean field theory, we establish an aggregated risk mean field that contains information of all risk-spreading particles by proposing a spatio-temporal model named HiRES risk map. It has dynamic fine spatial resolution and high computation efficiency enabling fast update. We then propose an objective individual epidemic risk scoring model named HiRES-p based on HiRES risk maps, and use it to develop statistical inference and machine learning methods for detecting suspected epidemic-infected individuals. We conduct numerical experiments by applying the proposed methods to study the early outbreak of COVID-19 in China. Results show that the HiRES risk map has strong ability in capturing global trend and local variability of the epidemic risk, thus can be applied to monitor epidemic risk at country, province, city and community levels, as well as at specific high-risk locations such as hospital and station. HiRES-p score seems to be an effective measurement of personal epidemic risk. The accuracy of both detecting methods are above 90\% when the population infection rate is under 20\%, which indicates great application potential in epidemic risk prevention and control practice.