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The onset of frictional motion is mediated by rupture-like slip fronts, which nucleate locally and propagate eventually along the entire interface causing global sliding. The static friction coefficient is a macroscopic measure of the applied force at this particular instant when the frictional interface loses stability. However, experimental studies are known to present important scatter in the measurement of static friction; the origin of which remains unexplained. Here, we study the nucleation of local slip at interfaces with slip-weakening friction of random strength and analyze the resulting variability in the measured global strength. Using numerical simulations that solve the elastodynamic equations, we observe that multiple slip patches nucleate simultaneously, many of which are stable and grow only slowly, but one reaches a critical length and starts propagating dynamically. We show that a theoretical criterion based on a static equilibrium solution predicts quantitatively well the onset of frictional sliding. We develop a Monte-Carlo model by adapting the theoretical criterion and pre-computing modal convolution terms, which enables us to run efficiently a large number of samples and to study variability in global strength distribution caused by the stochastic properties of local frictional strength. The results demonstrate that an increasing spatial correlation length on the interface, representing geometric imperfections and roughness, causes lower global static friction. Conversely, smaller correlation length increases the macroscopic strength while its variability decreases. We further show that randomness in local friction properties is insufficient for the existence of systematic precursory slip events. Random or systematic non-uniformity in the driving force, such as potential energy or stress drop, is required for arrested slip fronts. Our model and observations...