论文标题
使用改良的Windkessel模型，血压与动脉流量之间的关系
Relationship between blood pressure and flow rate in arteries using a modified Windkessel model
论文作者
论文摘要
这项研究使用改良的Windkessel模型检查了动脉的流量，考虑了各种血压模型。使用拉普拉斯变换方法得出了精确的溶液，并检查了血压对动脉流速的影响。还研究了流动阻力，动脉依从性和血液惯性对流量的影响。流速随血液和流动抗性的增加而降低，并降低了动脉依从性。次级峰的高度和位置是通过电阻，动脉依从性和血液惰性的结合来确定的。结果表明，高血压的风险可能会随着年龄的增长而增加，因为由于流动阻力的增加和动脉依从性的降低而导致的流量下降要比由于血液义能力降低而导致的流量增加更为实质性。提出的方法可以提供信息，以检查衰老，疾病和运动等因素如何影响血管流量。
This study examined the flow rate in arteries using the modified Windkessel model, considering various models for blood pressure. An exact solution was derived using a Laplace transform method and the effects of blood pressure on the flow rate in an artery were examined. The effects of the flow resistance, arterial compliance, and inertia of blood on the flow rate were also investigated. The flow rate decreased with increasing inertia of the blood and flow resistance and decreasing arterial compliance. The height and position of the secondary peak were determined by a combination of the flow resistance, arterial compliance, and blood inertance. The results suggest that the risk of hypertension may increase with age because decreases in flow rate due to an increase in flow resistance and a decrease in arterial compliance were more substantial than the increase in flow rate caused by a decrease in blood inertance. The proposed method can provide information to examine how factors, such as aging, disease, and exercise, affect the flow rate in blood vessels.
