论文标题

冠状病毒时间更安全的工作空间:抗体测试的新颖使用

Safer working spaces at coronavirus time: A novel use of antibody tests

论文作者

Foncea, Patricio, Mondschein, Susana, Massouh, Ragheb

论文摘要

SARS-COV-2大流行改变了世界运作的方式。健康问题和人口安全使国家的经济陷入了批判状态。因此,在确保工人安全的同时维持经济活动已成为全球目标。在本文中,我们提出了基于快速抗体测试(ABT)的新型安全方案。使用离散事件模拟,我们评估了其在感染工人的累积数量,有效的生殖数量($ r_e $)和公司内的积极劳动力上的绩效。使用合成实验,我们表明ABT每周两次(ABT 3)表现最好,检测到5.7%的受感染工人,而没有应用ABT时为16.9%。 $ r_e $从1.75减少到0.84,公司内的活跃工人略有下降。对脱落期的持续时间和ABT的敏感性进行了敏感性分析,并得出了相同的定性结论。我们在智利酿酒厂应用了该协议:实施ABT 3协议时,最初$ R_E $ 1.3的估计减少到0.7,受感染工人的数量减少了27%。尽管ABT未被批准用于COVID-19诊断,但我们的研究表明,升级的安全标准已经可以在工作区中实施。

The SARS-CoV-2 pandemic has transformed the way that the world functions. Health issues and population safety have driven countries' economies to a critical state; therefore, sustaining economic activity while keeping workers safe has become a worldwide goal. In this paper, we present a novel safety protocol based on rapid antibody testing (ABT). Using discrete event simulation, we evaluated its performance on the cumulative number of infected workers, effective reproductive number ($R_e$), and active work force within a company. Using a synthetic experiment, we showed that ABT twice a week (ABT 3) performed the best, detecting 5.7% of infected workers, compared to 16.9% when no ABT was applied. $R_e$ was reduced from 1.75 to 0.84, with a slight decrease in the active workers within the firm. A sensitivity analysis on the duration of the shedding period and sensitivity of ABT was performed and led to the same qualitative conclusions. We applied this protocol in a Chilean winery: the estimation of the initial $R_e$ of 1.3 was reduced to 0.7 when the ABT 3 protocol was implemented, with a 27% decrease in the number of infected workers. Although ABT is not approved for COVID-19 diagnosis, our study shows that upgraded safety standards can already be implemented in workspaces.

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