论文标题
通过周期力解开双链块共聚物DNA
Unzipping of a double-stranded block copolymer DNA by a periodic force
论文作者
论文摘要
使用Monte Carlo模拟，我们研究了用$ -A_N-B_N- $重复单元解压缩双链块共聚物DNA的滞后。在这里，$ a $和$ b $分别代表具有两种键和三个键的两种不同类型的碱基对，$ 2N $代表一个单元中此类基础对的数量。 DNA的末端受到频率（$ω$）和振幅（$ g_0 $）的时间依赖性周期力，以使另一端固定。我们发现，静态力的平衡力 - 温度相图与DNA序列无关。对于周期性的情况，发现结果取决于块共聚物DNA序列以及周期力作用的基本对类型。我们观察到各种形状和尺寸的磁滞回路，并在低频和高频方面获得循环区域的尺度。
Using Monte Carlo simulations, we study the hysteresis in unzipping of a double stranded block copolymer DNA with $-A_n B_n-$ repeat units. Here $A$ and $B$ represent two different types of base pairs having two- and three-bonds, respectively, and $2n$ represents the number of such base pairs in a unit. The end of the DNA are subjected to a time dependent periodic force with frequency ($ω$) and amplitude ($g_0$) keeping the other end fixed. We find that the equilibrium force-temperature phase diagram for the static force is independent of the DNA sequence. For the periodic force case, the results are found to be dependent on the block copolymer DNA sequence and also on the base pair type on which the periodic force is acting. We observe hysteresis loops of various shapes and sizes and obtain the scaling of loop area both at low and high frequency regimes.
