论文标题
对脂质双层中细菌紫红素的二维顺序的横向耗竭作用：基于二元硬盘模型的理论研究
Lateral depletion effect on two-dimensional ordering of bacteriorhodopsins in a lipid bilayer: A theoretical study based on a binary hard-disk model
论文作者
论文摘要
使用二进制硬盘模型研究了脂质双层中细菌紫红素的二维顺序。考虑到侧向耗竭效应，计算了相图。从相图获得了单体和三聚体的蛋白质排序的临界浓度。当考虑到消耗量（即脂质）之间的排斥核心相互作用时，临界浓度比与实验非常吻合。结果表明，耗竭作用在跨膜蛋白的关联行为中起重要作用。
The two-dimensional ordering of bacteriorhodopsins in a lipid bilayer was studied using a binary hard-disk model. The phase diagrams were calculated, taking into account the lateral depletion effects. The critical concentrations of the protein ordering for the monomers and the trimers were obtained from the phase diagrams. The critical concentration ratio agreed well with the experiment when the repulsive core interaction between the depletants, namely the lipids, was taken into account. The results suggest that the depletion effect plays an important role in the association behaviors of transmembrane proteins.
