论文标题
某些心血管危险因素对年龄和血压之间的相对率的影响
Influence of some cardiovascular risk factors on the rela-tionship between age and blood pressure
论文作者
论文摘要
血压（BP）是与心血管系统有关的生物学信号，不可避免地会受到衰老的影响。此外，它还受心血管危险因素的存在影响。为了评估BP与年龄之间的关系如何随着高血压和正常性受试者的危险因素的存在而变化，我们分析了880名具有和不吸烟的受试者，OBE-SITY，糖尿病，糖尿病和血脂异常。回归线拟合了每个BP/年龄关系，分别针对具有和没有危险因素的正常性和高血压受试者计算。对于四个条件中的每一个，办公室和24小时的门诊BP监测（ABPM）被考虑。在有和没有危险因素的受试者中，高血压的收缩压/年龄关系的斜率高于办公室和ABPM条件下的正常性受试者。此外，风险因素的存在通过使用办公室或ABPM测量值修改了高血压受试者中的收缩BP/年龄关系。最后，我们确认两种方式之间的差异也取决于年龄。
Blood Pressure (BP) is a biological signal related to the cardiovascular system that inevitably is affected by ageing. Moreover, it is also influenced by the presence of cardiovascular risk factors. To evaluate how the relationship be-tween BP and age changes with the presence of risk factors in hypertensive and normotensive subjects, we analyzed 880 subjects with and without smoking, obe-sity, diabetes mellitus and dyslipidemia. A regression line fitted each BP/Age relation calculated separately for normotensive and hypertensive subjects with and without risk factors. For each of the four conditions the office and the 24-hour ambulatory BP monitoring (ABPM) were considered. In subjects with and without risk factors, the slopes of the Systolic BP/Age relation were higher in hypertensive than in normotensive subjects in both office and ABPM conditions. Moreover, the presence of risk factors modified the Systolic BP/Age relation in hypertensive subjects by using either office or ABPM measurements. Finally, we confirmed that the difference between the two modalities depends on age too.
