论文标题
Terahertz生物组织对个性化医学的诊断和治疗的反应
Terahertz Response of Biological Tissue for Diagnostic and Treatment in Personalized Medicine
论文作者
论文摘要
提议针对个性化医学问题提出了基于硅纳米和硅（SNS）的光谱仪。 SNS结构表现出Terahertz（THZ）发射极的特性和生物组织THZ反应的接收器。测量SNS结构的电流 - 电压曲线使得可以分析生物组织的THz响应的光谱组成，并确定DNA寡核苷酸和相应化合物结构中包含的各种蛋白质和氨基酸的相对贡献。所提出的方法的明显优势与以下事实有关：THZ响应可以直接从活物生物组织中获得，因此用于对DNA寡核苷酸的表达分析。几个对照组的测试表明，对于个性化诊断和治疗方法，对SNS电流曲线的光谱峰的特定特征的进一步分析引起了人们的关注。
A spectrometer based on silicon nanosandwiches (SNS) is proposed for problems of personalized medicine. SNS structures exhibit properties of terahertz (THz) emitter and receiver of the THz response of biological tissue. Measurements of the current-voltage curves of the SNS structure make it possible to analyze the spectral composition of the THz response of biological tissue and determine relative contributions of various proteins and amino acids contained in the structure of DNA oligonucleotides and the corresponding compounds. Evident advantages of the proposed method are related to the fact that the THz response can be directly obtained from living biological tissue and, hence, used for express analysis of the DNA oligonucleotides. Tests of several control groups show that the further analysis of the specific features of the spectral peaks of the SNS current-voltage curves is of interest for methods of personalized diagnostics and treatment.
