论文标题
杂音非线性光学响应在上转换纳米颗粒中用于点传播功能工程
Heterochromatic nonlinear optical responses in upconversion nanoparticles for point spread function engineering
论文作者
论文摘要
发射极的点扩展功能（PSF）工程可以编码图像的更高空间频率信息以打破衍射极限，但遭受了复杂的光学系统的影响。在这里，我们提出了一种强大的策略，可以同时在单一坚固形状扫描光束下从上转换纳米颗粒中实现不同的PSF。通过使四光子状态饱和，可以通过甜甜圈发射PSF提取高频信息。相比之下，互补的较低频率信息可以由高斯样发射PSF执行，这是由于在两光子状态下过度饱和的结果。借助傅立叶域异质融合，我们验证了合成PSF覆盖低频和高频信息的能力，从而产生了整体增强的图像质量。我们显示的空间分辨率为40 nm，激发波长的1/24。这项工作提出了一种新的范围，用于开发非线性多色发射探针，以改善纳米镜检查中的图像质量和噪声控制。
Point spread function (PSF) engineering of the emitter can code higher spatial frequency information of an image to break diffraction limit but suffer from the complexed optical systems. Here we present a robust strategy to simultaneously achieve diverse PSFs from upconversion nanoparticles under a single doughnut-shape scanning beam. By saturating the four-photon state, the high-frequency information can be extracted through the doughnut emission PSF. In contrast, the complementary lower frequency information can be carried out by the Gaussian-like emission PSF, as a result of over-saturated at the two-photon state. With the Fourier domain heterochromatic fusion, we verify the capability of the synthesised PSF to cover both low and high-frequency information, yielding the overall enhanced image quality. We show a spatial resolution of 40 nm, 1/24th of the excitation wavelength. This work suggests a new scope for developing nonlinear multi-colour emitting probes to improve image quality and noise control in nanoscopy.
