论文标题
驱动聚合物转运到通道：ISO-Flux张力传播理论和Langevin动力学模拟
Driven polymer translocation into a channel: Iso-flux tension propagation theory and Langevin dynamics simulations
论文作者
论文摘要
使用ISO-FLUX张力传播（IFTP）理论和Langevin Dynamics（LD）模拟来研究通道驱动的聚合物易位的动力学，其中聚合物将聚合物转移到狭窄的通道中，并且在通道中的单体体验中的单体体验驱动力$ f _ _ {\ rm c} $。在高驱动力限制下，无论通道宽度如何，IFTP理论都预测$τ\ propto f _ {\ textrm {c}}}^ββ$在转运时间内，其中$β= -1 $是力缩放指数。此外，LD数据显示，对于仅拟合单个单体文件的非常狭窄的通道，由于通道内部的子链引起的熵力在易位动力学中没有重要作用，而力指数$β= -1 $无论力量幅度如何。随着通道宽度的增加，通道内部链的可能空间构型的数量变得很重要，并且所得的熵力导致力指数下降到统一以下。
Iso-flux tension propagation (IFTP) theory and Langevin dynamics (LD) simulations are employed to study the dynamics of channel-driven polymer translocation in which a polymer translocates into a narrow channel and the monomers in the channel experience a driving force $f_{\rm c}$. In the high driving force limit, regardless of the channel width, IFTP theory predicts $τ\propto f_{\textrm{c}}^β$ for the translocation time, where $β=-1$ is the force scaling exponent. Moreover, LD data show that for a very narrow channel fitting only a single file of monomers, the entropic force due to the subchain inside the channel does not play a significant role in the translocation dynamics, and the force exponent $β= -1$ regardless of the force magnitude. As the channel width increases the number of possible spatial configurations of the subchain inside the channel becomes significant, and the resulting entropic force causes the force exponent to drop below unity.
