论文标题
使用菌株弹性摄影术对足底软组织应力分布和溃疡和未拆除患者之间的同质性的定量比较
A quantitative comparison of plantar soft tissue strainability distribution and homogeneity between ulcerated and non-ulcerated patients using strain elastography
论文作者
论文摘要
这项研究的主要目的是开发一种可以准确定量足底软组织刚度分布和同质性的方法。这项研究的次要目的是研究软组织刚度分布和同质性的差异是否可以在溃疡和未拆除的脚之间检测到。开发了单个像素刚度的新型测量，称为定量应变性（QS）和相对应变性（RS）。从39（9例活跃的糖尿病足溃疡）患者获得糖尿病神经病患者的SE数据。活跃的糖尿病足溃疡的患者在第一个meta骨头和弹性措施的脚后跟以外的部分脚部受伤。 RS用于测量有或没有活性糖尿病足溃疡的参与者的足底软组织僵硬分布的变化和梯度。与未拆下组相比，溃疡组的底部上方方向上的足底软组织同质性在左前脚上方的上较高方向明显高（p <0.05）。对同质性的评估表明，可以进一步解释组织变化的性质，从而增加内部压力。这可能对评估糖尿病中软组织损伤和溃疡的脆弱性有影响。
The primary objective of this study was to develop a method that allows accurate quantification of plantar soft tissue stiffness distribution and homogeneity. The secondary aim of this study is to investigate if the differences in soft tissue stiffness distribution and homogeneity can be detected between ulcerated and non-ulcerated foot. Novel measures of individual pixel stiffness, named as quantitative strainability (QS) and relative strainability (RS) were developed. SE data obtained from 39 (9 with active diabetic foot ulcers) patients with diabetic neuropathy. The patients with active diabetic foot ulcer had wound in parts of the foot other than the first metatarsal head and the heel where the elastography measures were conducted. RS was used to measure changes and gradients in the stiffness distribution of plantar soft tissues in participants with and without active diabetic foot ulcer. The plantar soft tissue homogeneity in superior-inferior direction in the left forefoot was significantly (p<0.05) higher in ulcerated group compared to non-ulcerated group. The assessment of homogeneity showed potentials to further explain the nature of the change in tissue that can increase internal stress . This can have implications in assessing the vulnerability to soft tissue damage and ulceration in diabetes.
