论文标题
英格兰的痴呆症：量化和分析可修改风险
Dementia in England: Quantifying and analysing modifiable risk
论文作者
论文摘要
痴呆症的患病率将在整个21世纪爆炸。这种趋势已经开始在发达国家，将继续对全球公共卫生和社会护理服务施加巨大的压力。但是，在可预见的将来，无法治愈痴呆症，医学研究强调了降低痴呆症风险的潜力。如果在个人，临床和人口水平上解决某些危险因素，则可以预防超过三分之一的痴呆症病例。这项研究进一步探讨了这些可修改的危险因素，并通过使用复合指数来量化面部风险。该指数在国家卫生局临床委员会小组级别运作，以评估整个英格兰的空间差异。在该国北部和南部以及伦敦和该国的其余部分之间观察到明显的空间模式。这项研究中采用的框架为可以生成类似指数的牢固基础，有可能在更精细的空间决议下，结合了有关相关痴呆危险因素的更多知识的本地知识和数据。
The prevalence of dementia is set to explode throughout the 21st century. This trend has already started in developed countries and will continue to place heavy pressures on both public health and social care services across the world. No cure for dementia is likely within the foreseeable future, however, medical research highlights the potential to diminish the risk of dementia onset. Over one-third of dementia cases may be preventable if certain risk factors are addressed at the individual, clinical, and population level. This research further explores these modifiable risk factors and quantifies areal risk through the use of a composite index. The index operates at National Health Service Clinical Commission Group level to assess spatial differences across England. Clear spatial patterns are observed between the north and south of the country, and between London and the remainder of the country. The framework adopted in this research provides a firm foundation upon which similar indices could be produced, potentially at finer spatial resolutions, incorporating more informed local knowledge and data on relevant dementia risk factors.
