论文标题
使用闪烁玻璃检测器的蒙特卡洛模拟重建的PCT图像
Reconstructed pCT Images Using Monte Carlo Simulations of a Scintillating Glass Detector
论文作者
论文摘要
传统上与质子计算机断层扫描（PCT）相关的高成本和低图像质量使其无法在临床环境中看到大量使用。廉价，紧凑，高密度的玻璃探测器能够与现有的质子治疗相连，可能有助于解决这些问题。检测器的设计允许与单蛋白计数重建算法以及基于光束的算法结合使用，这些算法无法在加速器束中解析单个质子。这项研究介绍了使用辐射传输代码MCNP6从蒙特卡洛产生的PCT扫描的质子停止功率的定量重建图像，证明了使用该检测器设计的质子成像的可行性。使用两种重建算法重建的图像进行了检查并比较相对误差和对比度：一种标准过滤的反向注射算法作为基准，以及使用PCT算法的变体，它利用距离驱动式储备的概念。
The high cost and low image quality traditionally associated with proton computed tomography (pCT) have prevented it from seeing significant use in clinical settings. A cheap, compact, high-density scintillating glass detector capable of being attached to existing proton therapy gantries may help address these concerns. The design of the detector allows for use in conjunction with single-proton counting reconstruction algorithms, as well as beam-based algorithms that do not resolve individual protons within an accelerator bunch. This study presents quantitative reconstructed images of proton stopping power from Monte Carlo generated pCT scans using the radiation transport code MCNP6, demonstrating the feasibility of proton imaging using this detector design. Relative error and contrast have been examined and compared for images reconstructed using two reconstruction algorithms: a standard filtered backprojection algorithm to act as a benchmark, and a variant of a pCT algorithm which utilizes the concept of distance-driven binning.
