论文标题
使用简约模型和马尔可夫决策过程的流行病控制建模
Epidemic Control Modeling using Parsimonious Models and Markov Decision Processes
论文作者
论文摘要
许多国家 /地区至少经历了两波浪潮,即19009年的大流行。第二波更危险得多,因为不同的菌株似乎对人类健康有害,但它源于对第一波的自满。本文介绍了一个简约但代表性的随机流行模型,该模型可模拟该疾病的不确定传播,而不论潜伏期和恢复时间分布如何。我们还提出了马尔可夫决策过程,以寻求医疗体系使用和流行病的经济成本之间的最佳权衡。我们将该模型应用于来自印度新德里的Covid-19数据,并在不同的政策审查时间模拟流行病差异。结果表明,最佳政策迅速采取行动,以遏制第一波的流行,从而避免了医疗保健系统的崩溃和后爆发的未来成本。对第二次Covid-19浪潮期间印度医疗保健系统最近崩溃的分析表明,如果在第一波后促进了迅速缓解的情况下,可以保留许多生命。
Many countries have experienced at least two waves of the COVID-19 pandemic. The second wave is far more dangerous as distinct strains appear more harmful to human health, but it stems from the complacency about the first wave. This paper introduces a parsimonious yet representative stochastic epidemic model that simulates the uncertain spread of the disease regardless of the latency and recovery time distributions. We also propose a Markov decision process to seek an optimal trade-off between the usage of the healthcare system and the economic costs of an epidemic. We apply the model to COVID-19 data from New Delhi, India and simulate the epidemic spread with different policy review times. The results show that the optimal policy acts swiftly to curb the epidemic in the first wave, thus avoiding the collapse of the healthcare system and the future costs of posterior outbreaks. An analysis of the recent collapse of the healthcare system of India during the second COVID-19 wave suggests that many lives could have been preserved if swift mitigation was promoted after the first wave.