论文标题
常见的突触输入，协同作用和大小原理：移动生成的脊柱运动神经元的控制
Common Synaptic Input, Synergies, and Size Principle: Control of Spinal Motor Neurons for Movement Generation
论文作者
论文摘要
了解中枢神经系统如何控制运动仍然是一个重大挑战，并且关于该控制的基本特征的持续辩论。在这篇综述中，我们引入了一个新的概念框架，以分配脊柱运动神经元的共同输入。具体而言，该框架基于以下假设：1）基于他们收到的共同输入，将运动神经元分为官能团（簇）； 2）簇可能与运动神经元池的经典定义有明显不同，因此它们可能跨越肌肉和/或仅涉及一部分肌肉； 3）簇代表中枢神经系统使用的功能模块，以降低对照的维度； 4）无法实现接收共同输入的群集中单电机神经元的选择性自愿控制。我们讨论了该框架及其基本的理论和实验证据。
Understanding how movement is controlled by the central nervous system remains a major challenge, with ongoing debate about basic features underlying this control. In this review, we introduce a new conceptual framework for the distribution of common input to spinal motor neurons. Specifically, this framework is based on the following assumptions: 1) motor neurons are grouped into functional groups (clusters) based on the common inputs they receive; 2) clusters may significantly differ from the classical definition of motor neuron pools, such that they may span across muscles and/or involve only a portion of a muscle; 3) clusters represent functional modules used by the central nervous system to reduce the dimensionality of the control; and 4) selective volitional control of single motor neurons within a cluster receiving common inputs cannot be achieved. We discuss this framework and its underlying theoretical and experimental evidence.
