论文标题
在压缩下对骨软组织中3D位移的体内定量：基于2D的美国测量与压力溃疡风险评估的相关性
In vivo quantification of 3D displacement in sacral soft tissues under compression: Relevance of 2D US-based measurements for pressure ulcer risk assessment
论文作者
论文摘要
目的：最近研究了2D超声（US）成像作为3D磁共振成像（MRI）的一种更容易获得的替代方案，用于估计外部机械负载下的软问题运动。在预防压力溃疡的背景下，该试验MRI研究的目的是设计一个实验，以表征在受控的机械负载下s骨软组织运动。这样的实验是针对使用2D成像方式（Echography）与使用A（参考）3D成像方式（MRI）评估的2D成像方式（Echography）与组织运动评估的组织运动之间差异的估计。方法：一种健康的男性志愿者参与了这项研究。设计并使用与美国传感器的3D打印副本一起设计并用于加载符合MRI兼容的定制设置。收集了五个MR图像，在卸载中收集了一个，其中1个在不同的加载配置中（400-1200 [G]）。然后，根据数字体积相关的结果提取了每个加载配置的3D位移字段。将组织运动分离为MRI坐标系统的X，Y，Z方向以及平面外和平面内部组件之间的比率，评估了所选目标区域的每个体素的每个体素的比率：平面外和平面内部位移之间的比率高于平面外部的比率，而不是1.6的一半，而不是1.6均高于1.6的范围，而不是1个均高于1的voxex，则该区域高于1次，而在所有范围内，均超过了1个。使用了400-800 [G]的负载。结论：不容易忽略的脱离平面组织的位移，因此应谨慎使用2D US成像以评估ac骨区域的组织运动。应进一步研究该应用程序的3D美国模式。
OBJECTIVE: 2D Ultrasound (US) imaging has been recently investigated as a more accessible alternative to 3D Magnetic Resonance Imaging (MRI) for the estimation of soft issue motion under external mechanical loading. In the context of pressure ulcer prevention, the aim of this pilot MRI study was to design an experiment to characterize the sacral soft tissue motion under a controlled mechanical loading. Such an experiment targeted the estimation of the discrepancy between tissue motion assessed using a 2D imaging modality (echography) versus tissue motion assessed using a (reference) 3D imaging modality (MRI).METHODS: One healthy male volunteer participated in the study. An MRI-compatible custom-made setup was designed and used to load the top region of the sacrum with a 3D-printed copy of the US transducer. Five MR images were collected, one in the unloaded and four in the different loaded configurations (400-1200 [g]). Then, a 3D displacement field for each loading configuration was extracted based on the results of digital volume correlation. Tissue motion was separated into the X, Y, Z directions of the MRI coordinate system and the ratios between the out-of-plane and in-plane components were assessed for each voxel of the selected region of interest.RESULTS: Ratios between the out-of-plane and in-plane displacement components were higher than 0.6 for more than half of the voxels in the region of interest for all load cases and higher than 1 for at least quarter of the voxels when loads of 400-800 [g] were used.CONCLUSION: The out-of-ultrasound-plane tissue displacement was not negligible, therefore 2D US imaging should be used with caution for the evaluation of the tissue motion in the sacrum region. The 3D US modality should be further investigated for this application.
