论文标题
部分可观测时空混沌系统的无模型预测
Stress percolation criticality of glass to fluid transition in active cell layers
论文作者
论文摘要
使用汇合细胞层的三维表示，我们将活性细胞层中的无定形固体到流体相变到二维（2D）位点渗透普遍性类别。重要的是，我们统一了两个与此转变相关的两种不同的，主要的途径。即（i）细胞 - 细胞粘附和（ii）主动牵引力。对于每种途径，我们独立地改变了相应的控制参数，并将重点放在新兴的机械应力模式上，因为单层从玻璃状到流体状状态。通过有限尺寸的缩放分析，我们的结果使我们在细胞层的应力发展中建立了玻璃状流体向流体样转变，并表明相关的临界性属于2D位点渗透普遍性类别。我们的发现为活动细胞层中的固体（玻璃状）对流体相变提供了新的视角，并可以弥合我们对活性物质中玻璃行为的理解，并在生物学过程中的潜在影响，例如伤口愈合，发育和癌症进展。
Using three-dimensional representation of confluent cell layers, we map the amorphous solid to fluid phase transition in active cell layers onto the two-dimensional (2D) site percolation universality class. Importantly, we unify two distinct, predominant, pathways associated with this transition; namely (i) cell-cell adhesion and (ii) active traction forces. For each pathway, we independently vary the corresponding control parameter and focus on the emergent mechanical stress patterns as the monolayer transitions from a glassy- to a fluid-like state. Through finite-size scaling analyses, our results lead us to establish the glassy- to fluid-like transition as a critical phenomena in terms of stress development in the cell layer and show that the associated criticality belongs to the 2D site percolation universality class. Our findings offer a fresh perspective on solid (glass-like) to fluid phase transition in active cell layers and can bridge our understanding of glassy behaviors in active matter with potential implications in biological processes such as wound healing, development, and cancer progression.
