论文标题
使用超声凹痕和剪切波弹性图，构成参数鉴定跨态残留的肢体软组织
Constitutive parameter identification of transtibial residual limb soft tissue using ultrasound indentation and shear wave elastography
论文作者
论文摘要
有限元分析（FEA）可用于评估计算座舱设计的应用界面压力和内部组织应变。这种类型的框架需要现实的患者特定的肢体几何形状和本构特性。在最近的研究中，使用MRI衍生的3D患者几何形状的压痕和反FEA用于本构参数鉴定。但是，较长的计算时间和专业设备的使用给临床部署带来了挑战。在这项研究中，我们提出了一种新的方法，用于使用FEA，超声压痕和剪切波弹性弹力的组合来识别本构参数识别。在超声压痕实验期间，使用弹性学测量局部剪切模量对于残留肢体的生物力学建模具有特殊的意义，因为已知的软组织特性的区域依赖性（例如不同水平的疤痕和萎缩水平）。除了假体设计之外，这项工作还对肌肉健康和监测疾病进展的领域具有更大的影响。
Finite element analysis (FEA) can be used to evaluate applied interface pressures and internal tissue strains for computational prosthetic socket design. This type of framework requires realistic patient-specific limb geometry and constitutive properties. In recent studies, indentations and inverse FEA with MRI-derived 3D patient geometries were used for constitutive parameter identification. However, long computational times and use of specialized equipment presents challenges for clinical deployment. In this study, we present a novel approach for constitutive parameter identification using a combination of FEA, ultrasound indentation, and shear wave elastography. Local shear modulus measurement using elastography during an ultrasound indentation experiment has particular significance for biomechanical modeling of the residual limb since there are known regional dependencies of soft tissue properties such as varying levels of scarring and atrophy. Beyond prosthesis design, this work has broader implications to the fields of muscle health and monitoring of disease progression.
